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| Rank | Company Name | Market Capital | Headquarters Country |
| 1 | Eli Lilly | $808.65 B | United States |
| 2 | Novo Nordisk | $620.85 B | Denmark |
| 3 | Johnson & Johnson | $350.62 B | United States |
| 4 | Merck | $318.75 B | United States |
| 5 | AbbVie | $289.32 B | United States |
| 6 | Astrazeneca | $238.12 B | United Kingdom |
| 7 | Roche | $215.41 B | Switzerland |
| 8 | Novartis | $195.83 B | Switzerland |
| 9 | Amgen | $165.96 B | United States |
| 10 | Pfizer | $156.96 B | United States |
| 11 | Sanofi | $122.25 B | France |
| 12 | Vertex Pharmaceuticals | $121.35 B | United States |
| 13 | Regeneron Pharmaceuticals | $112.84 B | United States |
| 14 | CSL | $96.62 B | Australia |
| 15 | Gilead Sciences | $82.96 B | United States |
| 16 | Bristol-Myers Squibb | $81.20 B | United States |
| 17 | Zoetis | $80.12 B | United States |
| 18 | GlaxoSmithKline | $78.42 B | United Kingdom |
| 19 | CVS Health | $71.17 B | United States |
| 20 | Merck KGaA | $70.99 B | Germany |
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(updated on 4-July-2024)