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| Rank | Company Name | Market Capital | Headquarters Country |
| 1 | Eli Lilly | $719.95 B | United States |
| 2 | Novo Nordisk | $557.26 B | Denmark |
| 3 | Johnson & Johnson | $366.98 B | United States |
| 4 | Merck | $320.91 B | United States |
| 5 | AbbVie | $301.25 B | United States |
| 6 | Astrazeneca | $212.09 B | United Kingdom |
| 7 | Roche | $197.18 B | Switzerland |
| 8 | Novartis | $195.83 B | Switzerland |
| 9 | Pfizer | $151.64 B | United States |
| 10 | Amgen | $144.89 B | United States |
| 11 | Sanofi | $118.65 B | France |
| 12 | Bristol-Myers Squibb | $104.58 B | United States |
| 13 | Vertex Pharmaceuticals | $104.54 B | United States |
| 14 | Regeneron Pharmaceuticals | $103.60 B | United States |
| 15 | CVS Health | $92.46 B | United States |
| 16 | CSL | $96.64 B | United States |
| 17 | Gilead Sciences | $90.79 B | Australia |
| 18 | GlaxoSmithKline | $86.35 B | United States |
| 19 | Zoetis | $83.56 B | United Kingdom |
| 20 | Merck KGaA | $72.51 B | Germany |
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(updated on 10-Apr-2024)